2006 GMC Sierra 3500 Tune-Up Parts
160 parts verified to fit your 2006 GMC Sierra 3500 for a complete tune-up. This is an easy DIY project — estimated 1-2 hours.
Air Filters
(24)primary
aFe
aFe MagnumFLOW Air Filters OER P5R A/F P5R GM Diesel Trucks 06-10 V8-6.6L (td)
$104.00
K&N
K&N Universal Chrome Filter 6 inch FLG / 7.5 inch Base / 4.5 inch Top / 9 inch Height
$94.99
Fel-Pro
Fel-Pro Chevrolet Silverado 1500 Engine Camshaft Thrust Plate
$39.82
aFe
aFe MagnumFLOW Air Filters OER PDS A/F PDS GM Silverado/Sierra 99-12 V6/V8
$76.00
Banks Power
Banks Power Pre-Filter (for PN 42138)
$45.15
AEM Induction
AEM Silverado/Sierra/Avalanche/Tahoe/Yukon 12.625in O/S L x 10in O/S W x 1.75in H DryFlow Air Filter
$62.99
aFe
aFe MagnumFLOW Air Filters OER PG7 A/F PG7 GM Diesel Trucks 06-09 V8-6.6L (td)
$120.00
Airaid
Airaid 99-14 Chevy / GMC Silverado (All Engines) Direct Replacement Filter
$94.99
Fuel Injectors
(65)companion
Dee Zee
Deezee Universal Tanks - Combo Auxiliary Black Tread Aluminum (92 Gal)
$1883.48
Aeromotive
Aeromotive Fuel Pump - Diesel Lift Pump - 230 GPH
$1760.85
Fleece Performance
Fleece Performance 06-10 GM 2500/3500 Duramax LBZ/LMM High Pressure Injection Line (No. 2 & 7)
$87.03
Dee Zee
Deezee Universal Tanks - Square White Steel
$577.29
Fleece Performance
Fleece Performance 04.5-10 GM Duramax SureFlo Performance Sending Unit
$390.59
Dee Zee
Deezee Universal Tanks - L-Shape Brite-Tread Aluminum (111 Gal)
$1544.78
Fleece Performance
Fleece Performance 01-16 GM Duramax 2500/3500 Fuel Primer Bulb Sealing Kit
$54.39
Aeromotive
Aeromotive Fuel Pump - 01-10 Duramax Retro Fit Kit for 1/2in Lines
$1819.01
Fluids & Additives
(71)consumable
Yukon Gear & Axle
Yukon Gear Friction Modifier
$20.89
Royal Purple
Royal Purple HPS Synthetic High Performance Street 5W30 Motor Oil - 1 Quart
$59.94
LIQUI MOLY
LIQUI MOLY 1L Fully Synthetic Hypoid Gear Oil (GL5) LS SAE 75W140
$204.10
K&N
K&N Oil Filter Automotive 01-19 Chevrolet Silverado 6.6L
$10.99
Fleece Performance
Fleece Performance 01-05 GM 2500/3500 Duramax Replacement Transmission Line (LB7/LMM) - Long Line
$146.87
Motul
Motul 1L Synthetic Engine Oil 8100 5W40 X-CLEAN C3 -505 01-502 00-505 00-LL04
$147.53
LIQUI MOLY
LIQUI MOLY 205L Molygen New Generation Motor Oil SAE 5W30
$1866.84
Royal Purple
Royal Purple Max Gear Synthetic 75W90 Gear Oil (Canada) - 1 Quart
$101.94
Tune-Up for Other GMC Sierra 3500 Years
Other Jobs for Your 2006 GMC Sierra 3500
Frequently Asked Questions
What parts do I need for a tune-up on my 2006 GMC Sierra 3500?
A complete tune-up on the 2006 GMC Sierra 3500 typically requires air filters, fuel injectors, fluids & additives. All parts shown on this page are verified to fit your specific vehicle.
How long does a tune-up take on a 2006 GMC Sierra 3500?
A tune-up typically takes 1-2 hours and is rated as easy difficulty. Actual time may vary depending on your experience and the specific parts being replaced.
Can I do a tune-up myself?
Yes! A tune-up is an easy DIY project that most people can do with basic hand tools. It's a great way to save money on labor costs.
Are these parts guaranteed to fit my 2006 GMC Sierra 3500?
Yes, all parts on this page are verified to fit the 2006 GMC Sierra 3500 using VCDB fitment data from manufacturers. Our fitment information is cross-referenced with industry-standard vehicle databases to ensure accuracy.
What brands make tune-up parts for the 2006 GMC Sierra 3500?
We carry tune-up parts from trusted brands including aFe, K&N, Fel-Pro, Banks Power, and AEM Induction. Filter by brand to find your preferred manufacturer.
How much does a tune-up cost for a 2006 GMC Sierra 3500?
The cost of a tune-up for the 2006 GMC Sierra 3500 depends on the parts and brands you choose. Browse the parts on this page to see current pricing. Doing the work yourself saves significantly on labor costs.