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Pick your trim in My Garage — better matches across the catalog.
Start with an intent — drill into any category for exact-fit picks.
Maintenance & repair
Every category we carry for this vehicle, organized by system.
Find all the parts you need for common jobs on your 2022 Mercedes-Benz CLS450.
This page groups parts listed for the 2022 Mercedes-Benz CLS450. Some products fit every trim, while others depend on submodel, engine, drivetrain, or brake package. Use your trim in My Garage or the product page fitment check to confirm exact fit.
The most popular categories for the 2022 Mercedes-Benz CLS450 include Oil & Fluids, Brake Pads, Control Arms & Bushings, and Brake Rotors. Browse our full selection to find the exact parts you need for your vehicle.
Most in-stock items ship within 1-2 business days. Shipping rates are calculated at checkout based on your location.
Warranty coverage varies by manufacturer but typically ranges from 1 year to lifetime. Each product page includes specific warranty information from the manufacturer.
Mobil 1 V-Twin 20W-50 Synthetic Motorcycle Oil (1 Quart)
Fits any vehicle — oil, washes, waxes, and tools.
$7.08
$18.28
$40.01
$22.24
$11.84
$39.03
Everyday parts and care essentials — mats, covers, wipers, filters, and oils.
WeatherTech
Part # 4414942
$88.95
WeatherTech
Part # DE2211GY
$177.43
Hengst
Part # E3900LB
$39.43
Mobil 1
Part # 44925
Performance Tool
Part # W1
$29.43
WeatherTech
Part # 4514942
$88.95
WeatherTech
Part # DE2211CH
$168.95
K&N
Part # 33-3068
$76.47
$17.95
