52+ 2021 Mercedes-Benz CLS450 Brake Pads

4Matic · Brake Pads (52 products)

Exact-fit parts for the 2021 Mercedes-Benz CLS450 4Matic.

DFC 16-23 Mercedes-Benz E400 Front 5000 Advanced Ceramic Brake Pads

DFC

Part # 1551-1871-00

Fits your car

DFC 16-23 Mercedes-Benz E400 Front 5000 Advanced Ceramic Brake Pads

Position: Front
Pad: Ceramic

$70.65

DFC 17-25 Mercedes-Benz CLS450 Rear 4000 HybriDynamic Brake Pads and Hardware Kit

DFC

Part # 4000-2193-01

Fits your car

DFC 17-25 Mercedes-Benz CLS450 Rear 4000 HybriDynamic Brake Pads and Hardware Kit

Position: Rear
Hardware: Included

$41.34

DFC 16-23 Mercedes-Benz GLC43 AMG Front Euro 5000 Ceramic Brake Pads and Hardware Kit

DFC

Part # 1600-1871-01

Fits your car

DFC 16-23 Mercedes-Benz GLC43 AMG Front Euro 5000 Ceramic Brake Pads and Hardware Kit

Position: Front
Pad: Ceramic
Hardware: Included

$97.60

DFC 17-25 Mercedes-Benz GLC63 AMG S Rear Euro 5000 Ceramic Brake Pads

DFC

Part # 1600-2193-00

Fits your car

DFC 17-25 Mercedes-Benz GLC63 AMG S Rear Euro 5000 Ceramic Brake Pads

Position: Rear
Pad: Ceramic

$58.20

EBC 2019+ Mercedes-Benz CLS450 (C257) 3.0L Turbo Greenstuff Front Brake Pads

EBC

Part # DP23070

Fits your car

EBC 2019+ Mercedes-Benz CLS450 (C257) 3.0L Turbo Greenstuff Front Brake Pads

Position: Front

$198.05

PowerStop

Part # 16-1871

Fits your car

Power Stop 17-18 Mercedes-Benz C43 AMG Front Z16 Evolution Ceramic Brake Pads

Position: Front
Pad: Ceramic

$86.92

R1 2016-2023 Mercedes-Benz CLS450 Front R1 Ceramic Pads & Hardware Kit

R1 Concepts

Part # 2310-1871-01

Fits your car

R1 2016-2023 Mercedes-Benz CLS450 Front R1 Ceramic Pads & Hardware Kit

Position: Front
Pad: Ceramic
Hardware: Included

$67.17

DFC 16-23 Mercedes-Benz E450 Front 4000 HybriDynamic Brake Pads and Hardware Kit

DFC

Part # 4000-1871-01

Fits your car

DFC 16-23 Mercedes-Benz E450 Front 4000 HybriDynamic Brake Pads and Hardware Kit

Position: Front
Hardware: Included

$67.17

PowerStop

Part # Z23-2047

Fits your car

Power Stop 17-18 Mercedes-Benz E43 AMG Rear Z23 Evolution Sport Brake Pads w/Hardware

Position: Rear

$67.39

DFC 17-25 Mercedes-Benz CLS53 AMG Rear Euro 5000 Ceramic Brake Pads and Hardware Kit

DFC

Part # 1600-2193-01

Fits your car

DFC 17-25 Mercedes-Benz CLS53 AMG Rear Euro 5000 Ceramic Brake Pads and Hardware Kit

Position: Rear
Pad: Ceramic
Hardware: Included

$62.74

Pagid

Part # 355039221

Fits — 1 thing to check

Disc Brake Pad Set

$72.99

R1 Concepts

Part # 2000-1871-00

Fits your car

R1 16-23 Mercedes-Benz E43 AMG Front Track/Street Brake Pads

Position: Front

$38.66

EBC

Part # DP53070NDX

Fits your car

EBC 17-21 Mercedes-Benz C43 AMG (W205) 4Matic 3.0TT Bluestuff Front Brake Pads

Position: Front

$264.67

Holstein Parts

Part # 2BWS0007

Fits — 1 thing to check

Holstein Parts 2BWS0007 Disc Brake Pad Wear Sensor

$8.40

DFC

Part # 1600-1871-00

Fits your car

DFC 16-23 Mercedes-Benz E350 Front Euro 5000 Ceramic Brake Pads

Position: Front
Pad: Ceramic

$76.67

DFC

Part # 1551-2193-01

Fits your car

DFC 17-23 Mercedes-Benz E400 Rear 5000 Advanced Ceramic Brake Pads and Hardware Kit

Position: Rear
Pad: Ceramic
Hardware: Included

$62.74

Dynamic Friction

Part # 9512-63155

Fits your car

DFC Hi-Carbon Rotor - Drilled w/5000 Brake Pads & HW Kit

$347.70

PowerStop

Part # Z23-1871

Fits your car

PowerStop - Z23 Daily Driver Carbon-Fiber Ceramic Brake Pads with Hardware Kit

Pad: Carbon-fiber ceramic
Hardware: Included

$72.94

MPA

Part # 1001-1871C

Fits — 1 thing to check

Quality-Built Premium Ceramic Brake Pads

Pad: Ceramic

$53.78

EBC

Part # DP43070R

Fits your car

EBC 2017+ Mercedes-Benz E300 (W213) 2.0L Turbo Yellowstuff Front Brake Pads

Position: Front

$218.53

Frequently Asked Questions

Do these parts fit my 2021 Mercedes-Benz CLS450 4Matic?

This page groups parts listed for the 2021 Mercedes-Benz CLS450 4Matic. Some products fit every trim, while others depend on submodel, engine, drivetrain, or brake package. Use your trim in My Garage or the product page fitment check to confirm exact fit.

What brands make parts for the 2021 Mercedes-Benz CLS450 4Matic?

We carry parts from trusted brands including DFC, R1 Concepts, PowerStop, EBC, and Dynamic Friction, plus many more. Filter by brand to find your preferred manufacturer.

How fast do 2021 Mercedes-Benz CLS450 4Matic parts ship?

Most in-stock items ship within 1-2 business days. Shipping rates are calculated at checkout based on your location.

What warranty do your 2021 Mercedes-Benz CLS450 4Matic parts come with?

Warranty coverage varies by manufacturer but typically ranges from 1 year to lifetime. Each product page includes specific warranty information from the manufacturer.

2021 Mercedes-Benz CLS450(392 parts)

2021 Mercedes-Benz CLS450(392 parts)

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Other Mercedes-Benz CLS450 Years

4Matic · Brake Pads (52 products)

DFC 16-23 Mercedes-Benz E400 Front 5000 Advanced Ceramic Brake Pads

DFC 17-25 Mercedes-Benz CLS450 Rear 4000 HybriDynamic Brake Pads and Hardware Kit

DFC 16-23 Mercedes-Benz GLC43 AMG Front Euro 5000 Ceramic Brake Pads and Hardware Kit

DFC 17-25 Mercedes-Benz GLC63 AMG S Rear Euro 5000 Ceramic Brake Pads

EBC 2019+ Mercedes-Benz CLS450 (C257) 3.0L Turbo Greenstuff Front Brake Pads

Power Stop 17-18 Mercedes-Benz C43 AMG Front Z16 Evolution Ceramic Brake Pads

R1 2016-2023 Mercedes-Benz CLS450 Front R1 Ceramic Pads & Hardware Kit

DFC 16-23 Mercedes-Benz E450 Front 4000 HybriDynamic Brake Pads and Hardware Kit

Power Stop 17-18 Mercedes-Benz E43 AMG Rear Z23 Evolution Sport Brake Pads w/Hardware

DFC 17-25 Mercedes-Benz CLS53 AMG Rear Euro 5000 Ceramic Brake Pads and Hardware Kit

Disc Brake Pad Set

R1 16-23 Mercedes-Benz E43 AMG Front Track/Street Brake Pads

EBC 17-21 Mercedes-Benz C43 AMG (W205) 4Matic 3.0TT Bluestuff Front Brake Pads

Holstein Parts 2BWS0007 Disc Brake Pad Wear Sensor

DFC 16-23 Mercedes-Benz E350 Front Euro 5000 Ceramic Brake Pads

DFC 17-23 Mercedes-Benz E400 Rear 5000 Advanced Ceramic Brake Pads and Hardware Kit

DFC Hi-Carbon Rotor - Drilled w/5000 Brake Pads & HW Kit

PowerStop - Z23 Daily Driver Carbon-Fiber Ceramic Brake Pads with Hardware Kit

Quality-Built Premium Ceramic Brake Pads

EBC 2017+ Mercedes-Benz E300 (W213) 2.0L Turbo Yellowstuff Front Brake Pads

Frequently Asked Questions

Do these parts fit my 2021 Mercedes-Benz CLS450 4Matic?

What brands make parts for the 2021 Mercedes-Benz CLS450 4Matic?

How fast do 2021 Mercedes-Benz CLS450 4Matic parts ship?

What warranty do your 2021 Mercedes-Benz CLS450 4Matic parts come with?